Generously spread about 1/3 cup of the spice mixture evenly over the entire cut of brisket.
1/3 cup dry rub
Place brisket into the base of the crockpot, the fat side facing up. Brush with about 1/2 of the barbecue sauce.
4-5 pound brisket, 1 cup barbecue sauce
Cover and cook on low for 8-10 hours
Optional. Once the brisket is cooked thru and fork tender, preheat broiler to high heat. Remove the brisket and brush with the remaining sauce. Place under the broiler for about 5 minutes, until it gets a golden brown crust.
Once the brisket is cooked, let it rest for 5 minutes before using a sharp knife to slice against the grain.